4,4'-Dimethoxytrityl chlorideine simba nucleoside uye nucleotide boka rinodzivirira uye rinobvisa mumiririri.
Shoko rakafanana:DMT-Cl
Nhamba yeCAS:40615-36-9
Properties
Chemical Formula
Molecular Weight
Storage Temperature
Melting Point
Kuchena
Kunze
C21H19ClO2
338.82 g/mol
2~8℃
120-125 ℃
≥98%
Pink Crystalline
Sezvikamu zvakakosha zve nucleic acid cheni, nucleosides uye nucleotides inoita basa rakakosha mukufambiswa kweruzivo rwemajini.Nekudaro, nekuda kwekuita kwavo kemikari uye kushatisa kuri nyore, nucleosides uye nucleotides zvinoda mareagents akasarudzika kuti azvidzivirire panguva yekubatanidza.DMTCl4' Dimethoxytrityl (DMTCl) iboka rinoshanda zvakanyanya rinodzivirira nekubvisa iro rakashandura kuchengetedzwa kwemanucleosides uye nucleotides panguva yekugadzira.
DMTCl ihydroxyl inodzivirira iyo inosarudza kusangana nemapoka ehydroxyl emanucleosides uye nucleotides panguva yekubatanidza kuumba boka rekudzivirira kwenguva pfupi rinodzivirira nucleosides uye nucleotides kubva kune mamwe makemikari.Iri boka rekudzivirira renguva pfupi rinobviswa nyore nyore mushure mekugadzirwa, richisiya yakachena nucleosides kana nucleotides.
Nekuda kwekuita kwayo kwakanakisa uye kusarudza,DMTClinoshandiswa zvakanyanya seboka rinodzivirira uye rinobvisa mumiririri mukubatanidzwa kweDNA, RNA uye mamwe nucleic acids.Iyo inonyanya kubatsira kune oligonucleotide synthesis apo kunyatso kudzora pamusoro peiyo nucleotide chinzvimbo uye kutevedzana kunodiwa.
Pamusoro pekushanda semudziviriri weboka uye anobvisa, DMTCl ine simba hydroxyl inodzivirira nucleosides uye nucleotides.Inodzivirira mapoka e-hydroxyl e nucleosides uye nucleotides kubva kune oxidation, kuderedza, uye mamwe maitiro anogona kuvakuvadza panguva yekubatanidza.
Muchidimbu,DMTCl4 4' dimethoxytritylchinhu chakakosha chekugadzira nucleosides uye nucleotides.Yakanakisa reactivity, selectivity uye versatility inoita kuti ive boka rakanakira kuchengetedza uye kubvisa mumiriri uye hydroxyl inodzivirira mumiriri weDNA, RNA uye imwe nucleic acid synthesis.Kana iwe uchida kuchengetedzwa kwemhando yepamusoro uye yakavimbika yenyucleosides uye nucleotides panguva yekubatanidza, usatarise kupfuura DMTCl.
Nguva yekutumira: Jun-08-2023