Formamidine acetate, inozivikanwawo seN, N-dimethylformamidine acetate kana CAS No. 3473-63-0, inhengo inokosha inoita basa rinokosha mukugadzirwa kwezvinodhaka.Ichi chemikemikari chakwezva kutarisisa kukuru muindasitiri yemishonga nekuda kwezvivakwa zvaro zvakawanda uye zvinogona kurapa zvikumbiro.
Chimwe chezvinhu zvakakosha zve formamidine acetate kukwanisa kwayo kuita senheyo yakasimba uye nucleophile.Izvi zvinoreva kuti inogona kutora chikamu mukuita kwemakemikari, zvichiita kuti ive chinhu chakakosha mukugadzirwa kwemishonga yakawanda.Reactivity yayo yakasiyana-siyana inobvumira kuti ishandiswe mune zvakasiyana-siyana zvemishonga yemishonga, kusanganisira kugadzirwa kwemishonga inorwisa mabhakitiriya, antibacterial uye antifungal.
Formamidine acetateyakaratidza kugona kukuru semushonga unorwisa utachiona.Kuita kwayo kunopesana neDNA neRNA mavhairasi, kusanganisira herpes simplex virus (HSV) uye human immunodeficiency virus (HIV), yakadzidzwa zvakanyanya.Vatsvakurudzi vakaona kuti musanganiswa unodzivisa kudzokororwa kwehutachiwana nekupindira nehutachiona enzymes, nekudaro ichivharira kugona kwavo kuwanda mukati memasero anotambira.Tichifunga nezvekushushikana kuri kukura pamusoro pekubuda kwehutachiona uye kudiwa kweanoshanda antiviral marapirwo, formamidine acetate inotarisirwa kuve mukana wekugadzira riini antiviral mishonga.
Mukuwedzera, formamidine acetate yakaratidza simba reantimicrobial properties.Yakave ichidzidzwa nekuda kwekuita kwayo kunopesana nemhando dzakasiyana dzebhakitiriya, ese Gram-positive uye Gram-negative.Zvidzidzo zvakaratidza kuti komisheni iyi inogona kukanganisa bacterial cell membranes, ichitadzisa kukura kwebhakitiriya uye kuberekana.Yakawanikwa zvakare kuwedzera kushanda kwemishonga inorwisa mabhakitiriya iripo, zvichiita kuti ive mubatanidzwa mukurwisa utachiona husingaurayiwi nemishonga.
Imwe yakakosha application yeformamidine acetateinorara mukukwanisa kwayo antifungal.Utachiona hweFungal hunoisa njodzi huru kuhutano hwevanhu, kunyanya muvanhu vasina immunocompromised.Mushonga wacho wakaratidza migumisiro inovimbisa mukudzivisa kukura kwepathogenic fungi nekuvhiringidza masero avo membrane uye kukanganisa nzira dzavo dzemagetsi.Sezvo fungal kuramba kune ikozvino antifungal zvinodhaka zvinowedzera uye zvakanyanya kuwanda, formamidine acetate inopa nzira nyowani yekuvandudza antifungal mishonga.
Formamidine acetate inoshandiswawo sechinhu chinokosha chepakati mukugadzirwa kwemishonga yakawanda yemishonga.Yayo yakasarudzika kemikari chimiro uye reactivity inoita kuti ive yakakodzera mbishi zvinhu zvekugadzirwa kwemishonga yakasiyana.Uyezve, kuumbwa kwayo kwakanaka uye kuwanikwa kunobatsira mukuzivikanwa kwayo mukuvandudza zvinodhaka.
Mukupedzisa,formamidine acetateine CAS nhamba 3473-63-0 inoita basa rakakosha mukuvandudza zvinodhaka.Kugona kwayo kuita sehwaro hwakasimba uye nucleophile, pamwe neayo ane simba antiviral, antibacterial, uye antifungal properties, inoita kuti ive mumiriri anoyevedza wekuvandudzwa kwenovel therapeutic agents.Kuenderera mberi kwekuongorora kwe formamidine acetate mukutsvakurudza kwemishonga kunounza tariro huru yekuwanikwa kwezvinodhaka mune ramangwana uye kurapwa kwezvirwere zvakasiyana-siyana zvinotapukira.
Nguva yekutumira: Jun-20-2023